We're passionate about helping people achieve their healthiest, happiest skin. Whether you're struggling with acne, eczema, rosacea, or any other skin concern, we're here to offer support, information, and inspiration.
If you're considering lip filler, one of the first questions on your mind is probably: how long will this last? Here's everything you need to know about which lip fillers offer the longest-lasting results — and how to make the most of your treatment.
Fuller, more defined lips are one of the most popular cosmetic treatments available today. Modern lip fillers are safe, customizable, and minimally invasive. But with several product options available, patients often want to know which filler will give them the longest-lasting results before needing a touch-up.
At My Skin in St. Petersburg and Bradenton, Florida, our experienced providers help patients find the right filler for their unique lips, lifestyle, and longevity goals.

Most hyaluronic acid (HA) lip fillers — the gold standard in lip augmentation — last somewhere between 6 and 18 months. The exact duration depends on several factors: the specific product used, how much filler is injected, your metabolism, and how well you care for your skin after treatment.
Hyaluronic acid is a naturally occurring sugar molecule your body already produces. It works by attracting and binding water in the tissue, which creates that plump, hydrated look. Over time, your body gradually breaks down the HA — which is why results are temporary but also why they're reversible and very safe.
Pro Tip: Lips tend to metabolize filler faster than other facial areas because they're highly mobile — we talk, eat, and laugh with our lips constantly. Choosing a denser filler formulated specifically for lips is key to maximizing longevity.

At My Skin's cosmetic dermatology practice, we offer several premium lip filler options. Here's how they compare:
Restylane Kysse — 6 to 12 Months Restylane Kysse uses proprietary XpresHAn Technology to create a soft, flexible gel that moves naturally with the lips — avoiding a stiff or overfilled look. It also subtly enhances lip color and texture. Kysse is a top pick for patients who want natural-looking fullness that still allows expressive movement.
Versa — 6 to 12 Months Versa is formulated with uniform spherical particles for smooth, even distribution throughout the lip tissue. It's associated with less post-treatment swelling than some other fillers, making it a great choice for patients who want a comfortable recovery and a natural result.
Sculptra (Collagen Stimulator) — Up to 2 Years While Sculptra is primarily used for facial volume restoration, when used by an expert provider it can stimulate collagen around the lip area for longer-lasting softness and structure. It's not a traditional lip filler, but it can complement treatments — and results can last significantly longer than standard HA options.

The "longest-lasting" lip filler isn't necessarily the best choice for every patient. The ideal filler depends on your natural lip anatomy, the look you want to achieve, and how your body metabolizes HA. This is why a personalized consultation with a knowledgeable provider is so important.
Leah Michel, APRN FNP-BC, founder of My Skin, takes the time to evaluate your individual features and goals during every appointment. With her dermatology background and commitment to personalized care, she creates treatment plans tailored to you — never a one-size-fits-all approach.
Book a personalized lip filler consultation with Leah Michel, APRN FNP-BC at My Skin in St. Pete or Bradenton. We'll help you choose the right filler for your goals and create a customized plan just for you.
Request Your Appointment Online
St. Pete: (727) 295-7223 | Bradenton: (941) 330-5805
Even with the longest-lasting product, individual factors play a major role in how long you'll enjoy your results.
Your Metabolism People with faster metabolisms tend to break down hyaluronic acid more quickly. If you're very active or exercise frequently, you may notice results fading sooner than someone with a slower metabolic rate.
Amount of Filler Used More volume generally means a longer duration before a touch-up is needed. Your provider will recommend an appropriate amount based on your anatomy and goals during your consultation.
Sun Exposure & Lifestyle Excess UV exposure and habits like smoking can break down both collagen and hyaluronic acid faster. Protecting your skin and maintaining a healthy lifestyle helps preserve filler results longer. Explore the medical-grade skincare products available at My Skin to support your skin health between treatments.
Your Injector's Technique How filler is placed makes a meaningful difference. An expert injector who understands lip anatomy will place product precisely to maximize longevity and natural appearance. At My Skin, all injections are performed by trained, experienced professionals focused on beautiful, natural-looking results.
Maintenance Appointments Many patients find that scheduling a small touch-up before their filler fully dissolves — rather than waiting until it's completely gone — helps maintain a consistent look over time with less product needed at each visit.

While you can't stop your body from metabolizing HA over time, there are steps you can take to extend the life of your lip filler results:
Stay well hydrated — HA thrives on water, and good hydration helps maintain volume
Avoid prolonged sun exposure and always apply SPF to your lip area
Steer clear of smoking, which accelerates the breakdown of filler and collagen
Use medical-grade skincare products to support skin health from the outside in
Consider complementary treatments like microneedling or PRP injections that boost collagen and improve overall skin quality around the lips
The treatment process at My Skin is designed to be comfortable, quick, and effective. During your visit, your provider will discuss your enhancement goals in detail. A topical numbing cream is applied before any injections to keep you comfortable. The treatment itself takes about 30 to 45 minutes, and you can return to your normal activities right away.
You'll receive detailed aftercare instructions to help you get the best possible results. Minor swelling or bruising may occur but typically resolves within a few days. Most patients are thrilled with their results from the very first session.
Whether you're visiting our St. Petersburg location in Downtown St. Pete's Plaza Tower or our Bradenton office, you'll receive the same personalized, high-quality care that My Skin patients have come to expect.
How often do I need to get lip filler? Most patients come in for a touch-up every 6 to 12 months depending on the product used and how their body metabolizes it. Regular maintenance appointments help preserve a consistent, natural look over time.
Will my lips look fake if I get filler? Not with the right provider. At My Skin, Leah Michel's philosophy is always to enhance your natural features — not to overfill. The goal is beautiful, proportionate lips that look like the best version of you.
Is lip filler safe? When performed by a qualified healthcare professional, lip filler is generally very safe. Potential side effects like temporary bruising, swelling, or redness typically resolve within a few days. Your provider will discuss your full medical history and any contraindications before treatment.
Can lip filler be reversed? Yes. One of the great advantages of hyaluronic acid fillers is that they can be dissolved with an enzyme called hyaluronidase if you're ever unhappy with your results, giving patients tremendous peace of mind.
My Skin is a trusted medical and cosmetic dermatology practice serving St. Petersburg and Bradenton, Florida. Founded by Leah Michel, APRN FNP-BC, My Skin is built on the belief that great care starts with truly listening to each patient. Leah's combined dermatology and aesthetic training means your treatment isn't just beautiful — it's safe and medically sound.
In addition to lip fillers, My Skin offers a full suite of cosmetic treatments including Botox and Jeuveau, dermal fillers, Sculptra, microneedling, chemical peels, LED light therapy, and much more — all in a welcoming, supportive environment.
Ready to achieve fuller, more defined lips that last? The team at My Skin in St. Pete and Bradenton is here to help you find the perfect filler for long-lasting, natural-looking results.
Request Your Appointment Online
St. Pete: (727) 295-7223 | Bradenton: (941) 330-5805 | appointments@myskinbyleah.com
Disclaimer: This blog post is intended for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Individual results from lip filler treatments vary depending on factors such as the type of filler used, the amount injected, your metabolism, lifestyle, and overall health. All cosmetic procedures carry potential risks and side effects. Please consult with a qualified healthcare provider before undergoing any aesthetic treatment to determine what is appropriate for your individual needs and medical history. My Skin's services are performed by licensed medical professionals; however, this content should not be used as a substitute for professional medical consultation.
If you have any questions or concerns about your skin & would like to schedule an appointment at our St. Pete dermatology office or Brandenton dermatology office, please call us today!
111 2nd Ave NE., Suite 1406
St Petersburg, FL 33701
Plaza Tower- Downtown St Pete
Phone: (727) 295-7223
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